“I'd like you to take fewer supplements.”— The founder of a supplement company.
I'm Aaron Esagoff, MD, Johns Hopkins School of Medicine. I started ANTI Labs because this industry takes advantage of people who are trying to get healthier, and being bothered from a distance wasn't fixing anything.
I've always had an overdeveloped BS detector.
Medicine and research honed it, teaching me to ask “where's the evidence?” before believing anything. Then years of running my own studies, on brain injury in professional fighters, showed me how rare real, high-quality evidence is. Weak evidence dresses itself up as proof all the time. Some of the most eye-catching results of my research career are ones you'll never read. They wouldn't have survived honest scrutiny, so they stayed in the drawer. This industry publishes them anyway: single studies, funded by the seller, built backward from the claim on the label.
What you avoid matters more than what you add.
That's where the evidence lands. Nobody profits from telling you that, so we built a company on it. Before we sold anything, we reviewed a hundred of the most popular supplement ingredients against the evidence. Five survived. If that means you end up taking no supplements at all, good. I mean that. And for the short list worth taking, if you decide you want to, you'll have a source you never have to second-guess.
We named the company after what it refuses to be. The rest of this page is that refusal, in writing.
- Featured in
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- Medscape
- U.S. News & World Report
- Psychiatric Times
- Peer reviewer for
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- Sports Medicine
- The Physician and Sportsmedicine
- Frontiers in Neurology
- Frontiers in Neuroimaging
- Human Vaccines & Immunotherapeutics
Literature to lot number.
How a compound becomes an ANTI product. Every step is named, and every step leaves a record.
Literature review
Meta-analyses and human trials first. It has to work at a real dose, replicated across independent groups.
Formulary verdict
Approve or reject, and publish either way. Roughly 95 of 100 ingredients end here. The formulary →
Board review
Nine physicians sign the formulation on the record, and any of them can veto it. The advisory board →
Relentless sourcing
We compare certificates of analysis and forms until we find the best version, before we buy a single kilogram.
US manufacturing
Blended and packaged in a cGMP, NSF-certified California facility, to specifications we set and audit.
Independent verification
Every batch, not a sample, tested by an independent ISO 17025 lab for identity, purity, and safety.
Published proof
A QR code on every package opens that lot's certificate of analysis. The proof ships with the product. Look up a lot →
Scroll to run the gates
What we won't sell.
Every ingredient faces three gates. Fail one, we don't sell it. Watch what that does to a hundred:
Every ingredient faces three gates. Fail one, we don't sell it. Scroll, and watch the count.
Is it safe?
Decades of safe use in humans, or the review ends here.
Does it work?
Real results in humans, again and again.
Is this the best version of it?
A proven ingredient, in an optimal form, tested each and every time.
Safe and Effective, or we don't sell it.
Is it safe?
Decades of safe use in humans, or the review ends here.
Does it work?
Real results in humans, again and again.
Is this the best version of it?
A proven ingredient, in an optimal form, tested each and every time.
Safe and Effective, or we don't sell it.
Interactive · read along
How to read a supplement label.
Six moves the label makes on you. Watch each one happen, and you’ll spot it on any label after this.
Rented science
Exhibit · as seen on the label
“Clinically shown to boost daily energy.*”
* Study funded by the manufacturer. n=22. Not replicated.
The tell
One study, funded by the seller, never repeated. That’s marketing with a p-value.
P-hacking
You’re the brand. Run every test you can and wait for one to get lucky.
5 hit by pure chance. They print those. The other 91 go in a drawer you never see.
The tell
Ask what didn’t get published. The one result on the label had 90-odd silent failures behind it.
Mechanism theater
True: your microbiome matters. Here’s the leap the label makes from there.
Exhibit · as seen on the label
“50 billion live cultures, for a healthy gut”
The tell
“Gut bacteria matter” is true. “This strain helps you” is five gates further on, and the last two, no one can answer.
Empty claims
Real signal, or just noise? Tap your call on each one.
Claim 1 of 6 · as seen on a label
Non-GMO minerals
Magic doses
You already get most of this from food. Drag the dose and watch what “more” buys.
In the range your body can actually use.
The tell
More than your body needs is either flushed out or, for A and E, a real risk.
Candy dressed as health
Exhibit · as seen on the label
“30+ superfoods in every gummy: kale, spinach, broccoli, and more”
A 20g serving. Here’s where it actually goes:
Of a 20g serving: 8g sugar, 6g filler, 2.5g greens.
The “6g fiber” is starch filler, not the greens.
Now divide the greens by the label's brag
That’s about 1/12 of a single spinach leaf per “superfood.” The longer the list on the front, the less of anything is inside.
What one real serving of greens would cost you
96gof sugar
The greens are so diluted that reaching one actual serving takes 12 servings of this product. 12 servings is the part the “superfood” label never does the math on: 96g of sugar — about 24 teaspoons.
The tell
An ingredient on the list is not a dose in the serving. A tenth of a leaf does nothing, however good the leaf.
What I actually take.
Creatine monohydrate
CM-015-20 g daily.
Whey protein isolate
WP-0125-50 g daily.
Psyllium husk
FS-01 · In development10 g daily.
That's the entire routine. If a doctor selling supplements only takes three, that should tell you something about the other ninety-seven.
Founded by one doctor. Checked by nine.
Aaron formulates. He doesn't get the final word. Nothing ships without unanimous sign-off from nine independent physicians, named and on the record.
Meet the advisory board
Only What Works.Always The Best.
Two products carry the label so far. Everything behind them is published.