Creatine is one of the most studied compounds in sports nutrition, yet it remains underutilized by female athletes. The evidence is clear — creatine supports explosive output, mental sharpness, and muscular endurance.
CM-01Creatine Monohydrate
Creatine Monohydrate
The most premium creatine monohydrate on the market — pharmaceutical-grade, suspends invisibly, tastes like almost nothing.
Latest batch
Creatine Monohydrate
CM-01
26 MAY 2026
26 MAY 2026
IdentityPass
Heavy MetalsPass
MicrobialPass
More strength in the gym‡
More muscle, less fat‡
Sharper thinking when you're tired‡
Faster recovery between sets‡
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
5g
Daily
Standard protocol
The dose every clinical trial is built around. Fully saturates muscle within 3–4 weeks — take it any time, since saturation is cumulative.‡
10g
Daily
Enhanced protocol
Brain creatine uptake is slower than muscle, so cognitive benefits scale with dose. Pairs with heavy training and larger body mass; split into two 5 g doses if needed.‡
20g
1–5 days
Acute cognitive loading
A short window for sleep loss, jet lag, or high mental demand. Preserves reaction time and working memory when sleep is short. Split across the day.‡
How to take it
Mix 1 scoop (5 g) with at least 8 oz water or a protein shake. Fully soluble and taste-neutral.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Unanimously endorsed.
9-physician board · cleared Jan 2026
Hopkins · Harvard · Stanford · Mayo · UCSF · Penn · GW · Iowa
The record behind it
685+
Randomized human trials
25
Independent meta-analyses
Clinically studied since 1992
CM-01
Others
Pharma-grade purity, ≥99%
Grade often undisclosed
Strict limits on by-products (DCD)
Impurity levels rarely disclosed
Near-complete absorption, >99.9%
Pricier forms, no proven edge
Tested every lot — purity & heavy metals
Rarely tested per batch
Micronized — mixes clean, near-tasteless
Often coarse, sometimes bitter
One ingredient, no fillers
Often include unnecessary ingredients
Reviewed, formulated and signed off by physicians.
The research on creatine has broadened beyond athletes to cognition, bone density, and mood. CM-01 is built around that broader case.
Creatine is one of the few supplements I recommend without the usual caveats — the evidence is too strong to qualify.
Frequently Asked Questions
Do I need to load creatine?
No. Daily use saturates muscle stores in 3–4 weeks. A 20 g/day loading phase reaches saturation faster but offers no long-term advantage. Consistency matters more than anything.
Will it cause me to retain water or bloat?
Creatine pulls water into muscle cells, not under the skin. The small initial weight gain — typically 1–2 kg of intramuscular fluid — is the mechanism, not a side effect.
Monohydrate vs. HCl or ethyl ester — which form?
Monohydrate. Head-to-head trials of alternative salts find them equivalent at best, usually inferior on per-gram saturation. The premium forms exist to justify a margin story. We use Creatine Monohydrate — the form every major clinical trial has used.
Does creatine cause renal injury?
No. A 2025 systematic review and meta-analysis of 21 studies found no significant change in GFR or renal function markers from creatine supplementation. Long-term safety has been examined in controlled trials extending to five years. The original concern traces to two late-1990s case reports that have not been substantiated in subsequent prospective trials.
How should we interpret the serum creatinine elevation in supplementing patients?
Serum creatinine rises 10–20% from supplementation itself — a metabolic byproduct of creatine breakdown, not a damage marker. BUN, cystatin C, and the BUN:creatinine ratio remain unchanged, distinguishing supplementation-driven elevation from renal injury. For patients where renal monitoring is clinically important, cystatin-C-based eGFR avoids the creatinine confound.
Is it safe for my kidneys?
Yes, in healthy adults — examined in trials up to five years. Creatine slightly elevates serum creatinine, a metabolic byproduct that can confuse a routine panel without indicating damage. Tell your physician you supplement; with pre-existing renal disease, talk to them first.
Will creatine make me lose my hair?
No. A 2025 RCT directly measured hair follicle density and DHT over 12 weeks of creatine supplementation and found no difference from placebo. The original concern traces to a 2009 study in twenty rugby players that measured a transient DHT rise — but not hair loss — and the finding has not been replicated.
How should we counsel patients with stage 2–3 CKD?
We default to deferring — discuss with the patient's nephrologist before initiating. The literature in healthy populations doesn't extrapolate cleanly to compromised renal function, and serum creatinine elevations from supplementation can confound monitoring. For stage 1 with stable function and no other risk factors, baseline + 12-week eGFR and cystatin C are reasonable.
What's the sourcing standard and analytical purity for CM-01?
We source pharmaceutical-grade micronized creatine monohydrate at >99.9% by HPLC. Manufacturing-byproduct specifications include dicyandiamide ≤50 mg/kg, dihydrotriazine <3 mg/kg, and residual creatinine <100 mg/kg. Heavy metals (As, Cd, Pb, Hg) each at <0.1 mg/kg. Every incoming lot is re-verified via third-party ISO 17025 lab, with numerical results published on the lot registry.